In patients with severe acute cardiogenic shock, transcatheter edge-to-edge repair can reduce mitral regurgitation

In patients who arrive with severe acute cardiogenic shock, transcatheter edge-to-edge repair can lessen mitral regurgitation, according to a recent analysis published in the Journal of the American College of Cardiology.

Simard et al. conducted a study in conjunction with the American College of Cardiology and the Society of Thoracic Surgeons to better understand how TEER affects patients with cardiogenic shock (CS). The team looked at information from around 4,000 transcatheter edge-to-edge repair (TEER) patients with CS who had treatment between November 2013 and December 2021. A patient who had CS at the time of the procedure or who needed to employ an inotrope or mechanical circulatory support was considered to have the condition. The median patient age was 73, and 59.5% of patients were men.

Device success was observed in 85.6% of patients, with functional mitral regurgitation (MR) patients reporting a success rate of 87.2%, degenerative MR patients 83.7%, and mixed MR patients 88.6%.

Researchers analyzed echocardiographic data from each patient, observing that those in the device failure group had a reduced prevalence of moderate-severe MR or severe MR and a higher baseline left ventricular ejection fraction (LVEF).

Success with the device was linked to substantially lower 30-day and in-hospital mortality as well as shorter stays. Though single leaflet device attachment was more probable for the device failure group, most complication rates were comparable between the device success and device failure groups. The team also discovered that after a year, lower rates of hospitalization for heart failure and mortality were continuously linked to device success.
Source: Cardiovascular Business